Italy's Best has a Pompeii and Mount Vesuvius Day Trip including a private driver who will pick you up from your hotel, a tour of Vesuvius National Park (when open), and a tour of Pompeii where you can see first-hand the preserved remains of the city. You will also have time to explore on your own before meeting your driver to return home. The tour can be booked online at italysbestrome.com.
Dark Rome also has a day trip from Rome to Pompeii and Mt. Vesuvius. This tour will also bring you to the most interesting parts of the city, from the plaster death casts to streets cut out by carriage wheels 2,000 years ago. You will then be given the opportunity to climb to the ridge of the crater of Mt. Vesuvius with stops along the way to check out the view of the Bay of Naples below.
When the weather conditions force Mt. Vesuvius to close, Dark Rome will instead take you to the Naples National Archaeological Museum to view artifacts excavated from Pompeii and Herculaneum. This tour begins at $183. For more information, visit darkrome.com.