The tiny space manages to hold a fairly wide variety of stuff. Museum is all about weird collections, and the current roster of exhibit includes everything from personal objects once owned by notorious Screw magazine founder Al Goldstein, a roundup of fake vomits, and a series of weird brands of toothpaste. To save space, there are no explanations listed for any of the objects. There's a toll-free number that you can call to get information on specific pieces (each is labeled with a four-digit number).
If you really are determined to go to a museum with important historical artifacts, Museum can help with that. The shoe that hit President George W. Bush is there, improbably, in a glass box next to some stuff stolen from hotels. As they say - only in New York, kids.