2. Get Detailed Directions: Wherever you're going, get exact directions. A lot of the smaller hotels are on little side streets that taxi drivers won't necessarily know, so be sure to ask for more than just the street name.
3. Prices are Fair: Bargaining's not a big thing here, but neither is gouging tourists. With the exception of the seemingly unavoidable tourist-price-fare from the international airport into town, everyone seemed to give us a fair price without any hassle.
4. Airplanes Trump Chicken Buses: The domestic airlines (Air Panama and Aeroperlas) are cheap, reliable, and perfectly fine if you don't get freaked out by teeny tiny aircrafts. We've heard very mixed things about the buses – some people love the air-conditioned, overnight express bus from Panama City to Bocas; others paid an express fare and somehow still ended up on the chicken bus.
5. Skip Calle Uruguay: A lot of Panama City hoteliers will point tourists to Calle Uruguay in Bella Vista as the city's most interesting stop for food and nightlife. It is, but only if you're looking to grab some wings at Hooters and then hit up an American-style nightclub. Nearby Via Argentina has a more laid-back, local vibe.